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Hypoxia and Hypoxia-Inducible Factor-1α Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells: Implications of Endoplasmic Reticulum Stress for Extracellular Matrix Secretion.
Novais, Emanuel J; Choi, Hyowon; Madhu, Vedavathi; Suyama, Kaori; Anjo, Sandra I; Manadas, Bruno; Shapiro, Irving M; Salgado, António J; Risbud, Makarand V.
Afiliação
  • Novais EJ; Department of Orthopedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; Graduate Program in Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania; Life and Health Sciences Research Institute, School of Medici
  • Choi H; Department of Orthopedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; Graduate Program in Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Madhu V; Department of Orthopedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; Graduate Program in Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Suyama K; Department of Orthopedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; Department of Anatomy and Cellular Biology, Tokai University School of Medicine, Isehara, Japan.
  • Anjo SI; Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • Manadas B; Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • Shapiro IM; Department of Orthopedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; Graduate Program in Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.
  • Salgado AJ; Life and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal; Life and Health Sciences Research Institute/Biomaterials, Biodegradables and Biomimetics (ICVS/3B's) - PT Government Associate Laboratory, Braga, Portugal.
  • Risbud MV; Department of Orthopedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; Graduate Program in Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: makarand.risbud@jefferson.edu.
Am J Pathol ; 191(3): 487-502, 2021 03.
Article em En | MEDLINE | ID: mdl-33307037
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas da Matriz Extracelular / Subunidade alfa do Fator 1 Induzível por Hipóxia / Matriz Extracelular / Estresse do Retículo Endoplasmático / Núcleo Pulposo / Hipóxia Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas da Matriz Extracelular / Subunidade alfa do Fator 1 Induzível por Hipóxia / Matriz Extracelular / Estresse do Retículo Endoplasmático / Núcleo Pulposo / Hipóxia Idioma: En Ano de publicação: 2021 Tipo de documento: Article