ERG1 plays an essential role in rat cardiomyocyte fate decision by mediating AKT signaling.

Wang, Duo; Liu, Chang; Liu, Huan; Meng, Yilei; Lin, Fang; Gu, Yanqiong; Wang, Hanrui; Shang, Mengyue; Tong, Chang; Sachinidis, Agapios; Ying, Qilong; Li, Li; Peng, Luying

Wang, Duo; Liu, Chang; Liu, Huan; Meng, Yilei; Lin, Fang; Gu, Yanqiong; Wang, Hanrui; Shang, Mengyue; Tong, Chang; Sachinidis, Agapios; Ying, Qilong; Li, Li; Peng, Luying.

Afiliação

Wang D; Key Laboratory of Arrhythmias, Ministry of Education of China, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Liu C; Heart Health Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Liu H; Institute of Medical Genetics, Tongji University, Shanghai, People's Republic of China.
Meng Y; Key Laboratory of Arrhythmias, Ministry of Education of China, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Lin F; Heart Health Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Gu Y; Institute of Medical Genetics, Tongji University, Shanghai, People's Republic of China.
Wang H; Key Laboratory of Arrhythmias, Ministry of Education of China, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Shang M; Heart Health Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Tong C; Institute of Medical Genetics, Tongji University, Shanghai, People's Republic of China.
Sachinidis A; Key Laboratory of Arrhythmias, Ministry of Education of China, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Ying Q; Heart Health Center, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Li L; Institute of Medical Genetics, Tongji University, Shanghai, People's Republic of China.
Peng L; Key Laboratory of Arrhythmias, Ministry of Education of China, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.

Stem Cells ; 39(4): 443-457, 2021 04.

Article em En | MEDLINE | ID: mdl-33426760

Assuntos

Canal de Potássio ERG1/genética; Células-Tronco Embrionárias/metabolismo; Regulação da Expressão Gênica no Desenvolvimento; Integrina beta1/genética; Miócitos Cardíacos/metabolismo; Proteínas Proto-Oncogênicas c-akt/genética; Animais; Apoptose/genética; Diferenciação Celular; Classe Ia de Fosfatidilinositol 3-Quinase/genética; Classe Ia de Fosfatidilinositol 3-Quinase/metabolismo; Canal de Potássio ERG1/metabolismo; Embrião de Mamíferos; Células-Tronco Embrionárias/citologia; Fator de Transcrição GATA4/genética; Fator de Transcrição GATA4/metabolismo; Glicogênio Sintase Quinase 3 beta/genética; Glicogênio Sintase Quinase 3 beta/metabolismo; Quinase I-kappa B/genética; Quinase I-kappa B/metabolismo; Integrina beta1/metabolismo; Miócitos Cardíacos/citologia; NF-kappa B/genética; NF-kappa B/metabolismo; Fosforilação; Proteínas Proto-Oncogênicas c-akt/metabolismo; Proteínas Proto-Oncogênicas c-bcl-2/genética; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Ratos; Transdução de Sinais; beta Catenina/genética; beta Catenina/metabolismo

Palavras-chave

cardiac; cell biology; cell signaling; differentiation; embryoid bodies; embryonic stem cells; mesoderm

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica no Desenvolvimento / Integrina beta1 / Miócitos Cardíacos / Proteínas Proto-Oncogênicas c-akt / Células-Tronco Embrionárias / Canal de Potássio ERG1 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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