Healthcare utilization and economic burden of difficult-to-treat rheumatoid arthritis: a cost-of-illness study.
Rheumatology (Oxford)
; 60(10): 4681-4690, 2021 10 02.
Article
em En
| MEDLINE
| ID: mdl-33502493
ABSTRACT
OBJECTIVES:
To determine the impact of difficult-to-treat rheumatoid arthritis (D2T RA) on (costs related to) healthcare utilization, other resource use and work productivity.METHODS:
Data regarding healthcare utilization, other resource use and work productivity of 52 D2T (according to the EULAR definition) and 100 non-D2T RA patients were collected via a questionnaire and an electronic patient record review during a study visit. Annual costs were calculated and compared between groups. Multivariable linear regression analysis was performed to assess whether having D2T RA was associated with higher costs.RESULTS:
Mean (95% CI) annual total costs were 37 605 (27 689 - 50 378) for D2T and 19 217 (15 647 - 22 945) for non-D2T RA patients (P<0.001). D2T RA patients visited their rheumatologist more frequently, were more often admitted to day-care facilities, underwent more laboratory tests and used more drugs (specifically targeted synthetic DMARDs), compared with non-D2T RA patients (P<0.01). In D2T RA patients, the main contributors to total costs were informal help of family and friends (28%), drugs (26%) and loss of work productivity (16%). After adjustment for physical functioning (HAQ), having D2T RA was no longer statistically significantly associated with higher total costs. HAQ was the only independent determinant of higher costs in multivariable analysis.CONCLUSIONS:
The economic burden of D2T RA is significantly higher than that of non-D2T RA, indicated by higher healthcare utilization and higher annual total costs. Functional disability is a key determinant of higher costs in RA.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Aceitação pelo Paciente de Cuidados de Saúde
/
Custos de Cuidados de Saúde
/
Efeitos Psicossociais da Doença
/
Estresse Financeiro
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article