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Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease.
Somineni, Hari K; Nagpal, Sini; Venkateswaran, Suresh; Cutler, David J; Okou, David T; Haritunians, Talin; Simpson, Claire L; Begum, Ferdouse; Datta, Lisa W; Quiros, Antonio J; Seminerio, Jenifer; Mengesha, Emebet; Alexander, Jonathan S; Baldassano, Robert N; Dudley-Brown, Sharon; Cross, Raymond K; Dassopoulos, Themistocles; Denson, Lee A; Dhere, Tanvi A; Iskandar, Heba; Dryden, Gerald W; Hou, Jason K; Hussain, Sunny Z; Hyams, Jeffrey S; Isaacs, Kim L; Kader, Howard; Kappelman, Michael D; Katz, Jeffry; Kellermayer, Richard; Kuemmerle, John F; Lazarev, Mark; Li, Ellen; Mannon, Peter; Moulton, Dedrick E; Newberry, Rodney D; Patel, Ashish S; Pekow, Joel; Saeed, Shehzad A; Valentine, John F; Wang, Ming-Hsi; McCauley, Jacob L; Abreu, Maria T; Jester, Traci; Molle-Rios, Zarela; Palle, Sirish; Scherl, Ellen J; Kwon, John; Rioux, John D; Duerr, Richard H; Silverberg, Mark S.
Afiliação
  • Somineni HK; Genetics and Molecular Biology Program, Emory University, Atlanta, GA 30322, USA; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
  • Nagpal S; Center for Integrative Genomics, Georgia Institute of Technology, Atlanta, GA 30332, USA.
  • Venkateswaran S; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
  • Cutler DJ; Department of Human Genetics, Emory University, Atlanta, GA 30322, USA.
  • Okou DT; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine & Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
  • Haritunians T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Simpson CL; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
  • Begum F; Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Datta LW; Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Quiros AJ; Department of Pediatrics, Medical University of South Carolina, Pediatric Center for Inflammatory Bowel Disorders, Summerville, SC 29485, USA.
  • Seminerio J; Department of Gastroenterology, Medical University of South Carolina Digestive Disease Center, Charleston, SC 29425, USA.
  • Mengesha E; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Alexander JS; Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.
  • Baldassano RN; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Dudley-Brown S; Department of Medicine, Johns Hopkins University Schools of Medicine & Nursing, Baltimore, MD 21205, USA.
  • Cross RK; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Dassopoulos T; Baylor Scott and White Center for Inflammatory Bowel Diseases, Texas A&M University, Dallas, TX 75202, USA.
  • Denson LA; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Dhere TA; Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Iskandar H; Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Dryden GW; Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
  • Hou JK; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Hussain SZ; Department of Pediatrics, Willis-Knighton Physician Network, Shreveport, LA 71101, USA.
  • Hyams JS; Connecticut Children's Medical Center, Hartford, CT 06106, USA.
  • Isaacs KL; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Kader H; Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Kappelman MD; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
  • Katz J; Case Western Reserve University, Cleveland, OH 44106, USA.
  • Kellermayer R; Section of Pediatric Gastroenterology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX 77030, USA.
  • Kuemmerle JF; Division of Gastroenterology, Hepatology and Nutrition, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, VA 23284, USA.
  • Lazarev M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Li E; Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY 11794, USA.
  • Mannon P; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
  • Moulton DE; Vanderbilt Children's Hospital, Nashville, TN 37232, USA.
  • Newberry RD; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Patel AS; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Pekow J; Department of Pediatrics, University of Chicago Comer Children's Hospital, Chicago, IL 60637, USA.
  • Saeed SA; Dayton Children's Hospital, Dayton, OH 45404, USA.
  • Valentine JF; University of Utah, Health Sciences, Salt Lake City, UT 84132, USA.
  • Wang MH; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA.
  • McCauley JL; John P. Hussman Institute for Human Genomics, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136 USA; The Dr. John T. Macdonald Foundation Department of Human Genetics, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
  • Abreu MT; Division of Gastroenterology, Department of Medicine, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA; Department of Microbiology and Immunology, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
  • Jester T; Department of Pediatrics, UAB Medicine, Birmingham, AL 35233, USA.
  • Molle-Rios Z; Pediatric Gastroenterology and Nutrition, Nemours duPont Hospital for Children, DE 19803, USA.
  • Palle S; Department of Pediatrics, Oklahoma University School of Medicine, Oklahoma City, OK 73104, USA.
  • Scherl EJ; Gastroenterology and Hepatology, Jill Roberts Center for IBD, Weill Cornell Medicine, New York, NY 10065, USA.
  • Kwon J; UT Southwestern Department of Internal Medicine, Dallas, TX 75390, USA.
  • Rioux JD; Department of Medicine, Université de Montréal and the Montreal Heart Institute Research Center, Montreal, QC H1Y3N1, Canada.
  • Duerr RH; Human Genetics, and Clinical and Translational Science, Pittsburgh, PA 15213, USA.
  • Silverberg MS; Department of Medicine, Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, ON M5T3L9, Canada.
Am J Hum Genet ; 108(3): 431-445, 2021 03 04.
Article em En | MEDLINE | ID: mdl-33600772

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Predisposição Genética para Doença / Receptores de Prostaglandina E Subtipo EP4 / Calbindina 2 Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Predisposição Genética para Doença / Receptores de Prostaglandina E Subtipo EP4 / Calbindina 2 Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos