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Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells.
Kritikou, Joanna S; Oliveira, Mariana Ms; Record, Julien; Saeed, Mezida B; Nigam, Saket M; He, Minghui; Keszei, Marton; Wagner, Arnika K; Brauner, Hanna; Sendel, Anton; Sedimbi, Saikiran K; Rentouli, Stamatina; Lane, David P; Snapper, Scott B; Kärre, Klas; Vandenberghe, Peter; Orange, Jordan S; Westerberg, Lisa S.
Afiliação
  • Kritikou JS; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Oliveira MM; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Record J; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Saeed MB; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Nigam SM; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • He M; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Keszei M; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Wagner AK; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Brauner H; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Sendel A; Department of Medicine, Solna, Division of Rheumatology, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Sedimbi SK; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Rentouli S; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Lane DP; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Snapper SB; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Kärre K; Gastroenterology Division, Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Vandenberghe P; Department of Microbiology Tumor and Cell Biology, Biomedicum C7, and.
  • Orange JS; Center for Human Genetics, University Hospital Leuven, Leuven, Belgium.
  • Westerberg LS; Department of Pediatrics, NewYork-Presbyterian Morgan Stanley Children's Hospital, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
JCI Insight ; 6(6)2021 03 22.
Article em En | MEDLINE | ID: mdl-33621210
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Wiskott-Aldrich / Degranulação Celular / Proteína da Síndrome de Wiskott-Aldrich / Granzimas Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Wiskott-Aldrich / Degranulação Celular / Proteína da Síndrome de Wiskott-Aldrich / Granzimas Idioma: En Ano de publicação: 2021 Tipo de documento: Article