Characteristics and clinical influence factors of arsenic species in plasma and their role of arsenic species as predictors for clinical efficacy in acute promyelocytic leukemia (APL) patients treated with arsenic trioxide.

Guo, Meihua; Zhou, Jin; Fan, Shengjin; Li, Limin; Chen, Hongzhu; Lin, Liwang; Zhao, Qilei; Wang, Xinyu; Liu, Wensheng; Wu, Zhiqiang; Hai, Xin

Guo, Meihua; Zhou, Jin; Fan, Shengjin; Li, Limin; Chen, Hongzhu; Lin, Liwang; Zhao, Qilei; Wang, Xinyu; Liu, Wensheng; Wu, Zhiqiang; Hai, Xin.

Afiliação

Guo M; Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhou J; Department of Hematology, Southern University of Science and Technology Hospital, Shenzhen, China.
Fan S; Department of Hematology, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Li L; Department of Hematology, Southern University of Science and Technology Hospital, Shenzhen, China.
Chen H; Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Lin L; Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhao Q; Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Wang X; Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Liu W; Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Wu Z; Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Hai X; Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Harbin, China.

Expert Rev Clin Pharmacol ; 14(4): 503-512, 2021 Apr.

Article em En | MEDLINE | ID: mdl-33678104

Assuntos

Antineoplásicos/administração & dosagem; Trióxido de Arsênio/administração & dosagem; Leucemia Promielocítica Aguda/tratamento farmacológico; Adolescente; Adulto; Idoso; Idoso de 80 Anos ou mais; Antineoplásicos/farmacocinética; Trióxido de Arsênio/farmacocinética; Criança; Cromatografia Líquida de Alta Pressão; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Espectrometria de Fluorescência; Resultado do Tratamento; Adulto Jovem

Palavras-chave

Arsenic trioxide; acute promyelocytic leukemia; arsenic concentration monitoring; arsenic species; efficacy prediction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Promielocítica Aguda / Trióxido de Arsênio / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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