Mechanistic origins of diverse genome rearrangements in cancer.

Dahiya, Rashmi; Hu, Qing; Ly, Peter

Dahiya, Rashmi; Hu, Qing; Ly, Peter.

Afiliação

Dahiya R; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Hu Q; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Ly P; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: peter.ly@utsouthwestern.edu.

Semin Cell Dev Biol ; 123: 100-109, 2022 03.

Article em En | MEDLINE | ID: mdl-33824062

Assuntos

Cromotripsia; Neoplasias; Aberrações Cromossômicas; Rearranjo Gênico/genética; Genoma; Humanos; Neoplasias/genética

Palavras-chave

Cancer genomes; Chromosome rearrangements; Chromothripsis; DNA damage; DNA repair; Genomic instability; Micronuclei; Mitosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromotripsia / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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