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Dual Sensory Impairment and Cognitive Impairment in the Korean Longitudinal Elderly Cohort.
Byeon, Gihwan; Oh, Gyu Han; Jhoo, Jin Hyeong; Jang, Jae-Won; Bae, Jong Bin; Han, Ji Won; Kim, Tae Hui; Kwak, Kyung Phil; Kim, Bong Jo; Kim, Shin Gyeom; Kim, Jeong Lan; Moon, Seok Woo; Park, Joon Hyuk; Ryu, Seung-Ho; Youn, Jong Chul; Lee, Dong Woo; Lee, Seok Bum; Lee, Jung Jae; Lee, Dong Young; Kim, Ki Woong.
Afiliação
  • Byeon G; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Oh GH; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Jhoo JH; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Jang JW; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Bae JB; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Han JW; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Kim TH; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Kwak KP; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Kim BJ; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Kim SG; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Kim JL; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Moon SW; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Park JH; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Ryu SH; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Youn JC; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Lee DW; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Lee SB; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Lee JJ; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Lee DY; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
  • Kim KW; From the Departments of Psychiatry (G.B., J.H.J.) and Neurology (J.-W.J.), Kangwon National University Hospital, Chuncheon; Public Health Medical Service (G.H.O.) and Department of Neuropsychiatry (D.Y.L.), Seoul National University Hospital; Department of Neuropsychiatry (J.B.B., J.W.H., K.W.K.), S
Neurology ; 96(18): e2284-e2295, 2021 05 04.
Article em En | MEDLINE | ID: mdl-33827964
OBJECTIVE: To investigate the effects of single sensory impairment (SSI; visual or auditory) or dual sensory impairment (DSI; visual and auditory) on dementia and longitudinal changes of neuropsychological test scores. METHODS: In this nationwide, prospective, community-based elderly cohort study, KLOSCAD (the Korean Longitudinal Study on Cognitive Aging and Dementia), 6,520 elderly individuals (58-101 years) representing the general population were included. We defined visual and auditory sensory impairment via self-report questionnaire: 932 had normal sensory function, 2,957 had an SSI, and 2,631 had a DSI. Demographic and clinical variables including cognitive outcomes were evaluated every 2 years over 6 years. Through logistic regression, Cox regression, and linear mixed model analysis, the relationship between SSI or DSI and dementia prevalence, dementia incidence, and change in neuropsychological scores were evaluated. RESULTS: At baseline, DSI was significantly associated with increased dementia prevalence compared to normal sensory function (odds ratio [OR] 2.17, 95% confidence interval [CI] 1.17-4.02), but SSI was not (OR 1.27, 95% CI 0.66-2.41). During the 6-year follow-up, the incidence of dementia was significantly higher in the DSI group than in the normal sensory function group (hazard ratio 1.9, 95% CI 1.04-3.46) and neuropsychological scores significantly decreased (ß -0.87, 95% CI [-1.17 to -0.58]). CONCLUSIONS: Our results suggest that coexisting visual and hearing impairments facilitate dementia prevalence, dementia incidence, and cognitive decline, but visual or hearing impairment alone do not. Visual and hearing impairment may lead to dementia or cognitive decline independent of Alzheimer pathology.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtornos da Visão / Disfunção Cognitiva / Perda Auditiva País/Região como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtornos da Visão / Disfunção Cognitiva / Perda Auditiva País/Região como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article