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Pharmacokinetics, safety, tolerability and efficacy of cotadutide, a glucagon-like peptide-1 and glucagon receptor dual agonist, in phase 1 and 2 trials in overweight or obese participants of Asian descent with or without type 2 diabetes.
Asano, Michiko; Sekikawa, Akiko; Kim, Hyosung; Gasser, Robert A; Robertson, Darren; Petrone, Marcella; Jermutus, Lutz; Ambery, Philip.
Afiliação
  • Asano M; Medical Science, BioPharmaceuticals TA, R&D, AstraZeneca K.K., Tokyo, Japan.
  • Sekikawa A; Clinical Science, BioPharmaceuticals TA, R&D, AstraZeneca K.K., Tokyo, Japan.
  • Kim H; Biometrics, Science & Data Analytics Division, R&D, AstraZeneca K.K., Osaka, Japan.
  • Gasser RA; Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Robertson D; Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), AstraZeneca, Cambridge, UK.
  • Petrone M; Clinical Pharmacology and Quantitative Pharmacology, AstraZeneca, Cambridge, UK.
  • Jermutus L; Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), AstraZeneca, Cambridge, UK.
  • Ambery P; Late-stage Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Diabetes Obes Metab ; 23(8): 1859-1867, 2021 08.
Article em En | MEDLINE | ID: mdl-33908687
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Glucagon / Diabetes Mellitus Tipo 2 Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Glucagon / Diabetes Mellitus Tipo 2 Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão