EZH2 regulates the malignancy of human glioblastoma cells via modulation of Twist mRNA stability.

Zhai, Xuan; Li, Lu-Sheng; Zhou, Yu-Dong; Ji, Wen-Yuan; Chen, Hui; Xiao, Han; Liang, Ping

Zhai, Xuan; Li, Lu-Sheng; Zhou, Yu-Dong; Ji, Wen-Yuan; Chen, Hui; Xiao, Han; Liang, Ping.

Afiliação

Zhai X; Department of Neurosurgery, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of
Li LS; Department of Neurosurgery, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of
Zhou YD; Department of Neurosurgery, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of
Ji WY; Department of Neurosurgery, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of
Chen H; Department of Neurosurgery, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of
Xiao H; Department of Neurosurgery, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of
Liang P; Department of Neurosurgery, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of

Eur J Pharmacol ; 904: 174177, 2021 Aug 05.

Article em En | MEDLINE | ID: mdl-34015321

Assuntos

Neoplasias Encefálicas/genética; Proteína Potenciadora do Homólogo 2 de Zeste/genética; Proteína Potenciadora do Homólogo 2 de Zeste/metabolismo; Glioblastoma/genética; MicroRNAs/genética; Proteínas Nucleares/genética; Proteína 1 Relacionada a Twist/genética; Neoplasias Encefálicas/metabolismo; Linhagem Celular Tumoral; Técnicas de Silenciamento de Genes; Glioblastoma/metabolismo; Histonas/metabolismo; Humanos; MicroRNAs/metabolismo; Proteínas Nucleares/metabolismo; Estabilidade de RNA/genética; Temozolomida/farmacologia; Proteína 1 Relacionada a Twist/metabolismo

Palavras-chave

EZH2; GBM; Malignancy; Migration; Twist

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Proteínas Nucleares / Glioblastoma / MicroRNAs / Proteína 1 Relacionada a Twist / Proteína Potenciadora do Homólogo 2 de Zeste Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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