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ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome.
Wu, Xiao-Yan; Lv, Jin-Yan; Zhang, Shi-Qing; Yi, Xin; Xu, Zi-Wei; Zhi, Yuan-Xing; Zhao, Bo-Xin; Pang, Jian-Xin; Yung, Ken Kin Lam; Liu, Shu-Wen; Zhou, Ping-Zheng.
Afiliação
  • Wu XY; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Lv JY; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Zhang SQ; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
  • Yi X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Xu ZW; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Zhi YX; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Zhao BX; Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Pang JX; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Yung KKL; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. kklyung@hkbu.edu.hk.
  • Liu SW; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. liusw@smu.edu.cn.
  • Zhou PZ; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. pzzhou@smu.edu.cn.
Acta Pharmacol Sin ; 43(4): 992-1000, 2022 Apr.
Article em En | MEDLINE | ID: mdl-34341510
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China