Fragment-type 4-azolylcoumarin derivatives with anticancer properties.

Simic, Milena; Petkovic, Milos; Jovanovic, Predrag; Jovanovic, Milos; Tasic, Gordana; Besu, Irina; Zizak, Zeljko; Aleksic, Ivana; Nikodinovic-Runic, Jasmina; Savic, Vladimir

Simic, Milena; Petkovic, Milos; Jovanovic, Predrag; Jovanovic, Milos; Tasic, Gordana; Besu, Irina; Zizak, Zeljko; Aleksic, Ivana; Nikodinovic-Runic, Jasmina; Savic, Vladimir.

Afiliação

Simic M; Department of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Petkovic M; Department of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Jovanovic P; Department of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Jovanovic M; Department of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Tasic G; Department of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Besu I; Department of Experimental Oncology, Institute of Oncology and Radiology of Serbia, Belgrade, Serbia.
Zizak Z; Department of Experimental Oncology, Institute of Oncology and Radiology of Serbia, Belgrade, Serbia.
Aleksic I; Laboratory for Eco-Biotechnology and Drug Development, Institute for Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
Nikodinovic-Runic J; Laboratory for Eco-Biotechnology and Drug Development, Institute for Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
Savic V; Department of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.

Arch Pharm (Weinheim) ; 354(11): e2100238, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34374111

Assuntos

Antineoplásicos/farmacologia; Cumarínicos/farmacologia; Neoplasias/tratamento farmacológico; Animais; Antineoplásicos/síntese química; Antineoplásicos/química; Ciclo Celular/efeitos dos fármacos; Linhagem Celular Tumoral; Cisplatino/farmacologia; Cumarínicos/síntese química; Cumarínicos/química; Feminino; Células HeLa; Humanos; Concentração Inibidora 50; Células K562; Células MCF-7; Masculino; Neoplasias/patologia; Relação Estrutura-Atividade; Testes de Toxicidade; Peixe-Zebra

Palavras-chave

anticancer properties; azoles; cell lines; coumarins; embryotoxicity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cumarínicos / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cumarínicos / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article