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Optimization of Naphthyridones into Selective TATA-Binding Protein Associated Factor 1 (TAF1) Bromodomain Inhibitors.
Clegg, Michael A; Theodoulou, Natalie H; Bamborough, Paul; Chung, Chun-Wa; Craggs, Peter D; Demont, Emmanuel H; Gordon, Laurie J; Liwicki, Gemma M; Phillipou, Alex; Tomkinson, Nicholas C O; Prinjha, Rab K; Humphreys, Philip G.
Afiliação
  • Clegg MA; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Theodoulou NH; WestCHEM, Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom.
  • Bamborough P; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Chung CW; WestCHEM, Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom.
  • Craggs PD; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Demont EH; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Gordon LJ; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Liwicki GM; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Phillipou A; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Tomkinson NCO; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Prinjha RK; GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, United Kingdom.
  • Humphreys PG; WestCHEM, Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom.
ACS Med Chem Lett ; 12(8): 1308-1317, 2021 Aug 12.
Article em En | MEDLINE | ID: mdl-34413961
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido