The BigBrainWarp toolbox for integration of BigBrain 3D histology with multimodal neuroimaging.
Elife
; 102021 08 25.
Article
em En
| MEDLINE
| ID: mdl-34431476
ABSTRACT
Neuroimaging stands to benefit from emerging ultrahigh-resolution 3D histological atlases of the human brain; the first of which is 'BigBrain'. Here, we review recent methodological advances for the integration of BigBrain with multi-modal neuroimaging and introduce a toolbox, 'BigBrainWarp', that combines these developments. The aim of BigBrainWarp is to simplify workflows and support the adoption of best practices. This is accomplished with a simple wrapper function that allows users to easily map data between BigBrain and standard MRI spaces. The function automatically pulls specialised transformation procedures, based on ongoing research from a wide collaborative network of researchers. Additionally, the toolbox improves accessibility of histological information through dissemination of ready-to-use cytoarchitectural features. Finally, we demonstrate the utility of BigBrainWarp with three tutorials and discuss the potential of the toolbox to support multi-scale investigations of brain organisation.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Software
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Encéfalo
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Imageamento Tridimensional
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Neuroimagem
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Canadá