Biotransformations of anthranilic acid and phthalimide to potent antihyperlipidemic alkaloids by the marine-derived fungus Scedosporium apiospermum F41-1.

Chen, Pei-Nan; Hao, Meng-Jiao; Li, Hou-Jin; Xu, Jun; Mahmud, Taifo; Lan, Wen-Jian

Chen, Pei-Nan; Hao, Meng-Jiao; Li, Hou-Jin; Xu, Jun; Mahmud, Taifo; Lan, Wen-Jian.

Afiliação

Chen PN; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China.
Hao MJ; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China.
Li HJ; School of Chemistry, Sun Yat-sen University, Guangzhou 510275, People's Republic of China.
Xu J; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China.
Mahmud T; Department of Pharmaceutical Sciences, Oregon State University, Corvallis, OR 97331, USA.
Lan WJ; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China. Electronic address: lanwj@mail.sysu.edu.cn.

Bioorg Chem ; 116: 105375, 2021 11.

Article em En | MEDLINE | ID: mdl-34563999

Assuntos

Alcaloides/química; Biotransformação; Hipolipemiantes/química; Ftalimidas/química; Scedosporium/química; ortoaminobenzoatos/química; Células 3T3-L1; Animais; Camundongos; Estrutura Molecular; Ftalimidas/síntese química; ortoaminobenzoatos/síntese química

Palavras-chave

3T3-L1 cells; Antihyperlipidemic; Biotransformations; Marine-derived fungus; Scedosporium apiospermum F41-1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ftalimidas / Biotransformação / Scedosporium / Alcaloides / Ortoaminobenzoatos / Hipolipemiantes Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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