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Long-Acting Tumor-Activated Prodrug of a TGFßR Inhibitor.
Zhang, Yong; Parrish, Karen E; Tortolani, David R; Poss, Michael A; Huang, Audris; Wan, Honghe; Purandare, Ashok V; Donnell, Andrew F; Kempson, James; Hou, Xiaoping; Pawluczyk, Joseph; Yip, Shiuhang; Luk, Emily; Raghavan, Nimmi; Swanson, Jesse; Smalley, James; Murtaza, Anwar; Yang, Zheng; Augustine-Rauch, Karen; Lombardo, Louis J; Borzilleri, Robert.
Afiliação
  • Zhang Y; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Parrish KE; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Tortolani DR; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Poss MA; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Huang A; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Wan H; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Purandare AV; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Donnell AF; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Kempson J; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Hou X; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Pawluczyk J; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Yip S; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Luk E; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Raghavan N; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Swanson J; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Smalley J; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Murtaza A; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Yang Z; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Augustine-Rauch K; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Lombardo LJ; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
  • Borzilleri R; Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.
J Med Chem ; 64(21): 15787-15798, 2021 11 11.
Article em En | MEDLINE | ID: mdl-34704759
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Receptor do Fator de Crescimento Transformador beta Tipo I / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Receptor do Fator de Crescimento Transformador beta Tipo I / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos