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The 40S-LARP1 complex reprograms the cellular translatome upon mTOR inhibition to preserve the protein synthetic capacity.
Fuentes, Pedro; Pelletier, Joffrey; Martinez-Herráez, Carolina; Diez-Obrero, Virginia; Iannizzotto, Flavia; Rubio, Teresa; Garcia-Cajide, Marta; Menoyo, Sandra; Moreno, Victor; Salazar, Ramón; Tauler, Albert; Gentilella, Antonio.
Afiliação
  • Fuentes P; Laboratory of Cancer Metabolism, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
  • Pelletier J; Laboratory of Cancer Metabolism, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
  • Martinez-Herráez C; Laboratory of Cancer Metabolism, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
  • Diez-Obrero V; Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona, Barcelona, Spain.
  • Iannizzotto F; Unit of Biomarkers and Susceptibility, Oncology Data Analytics Program, Catalan Institute of Oncology (ICO). Hospitalet de Llobregat, Barcelona, Spain.
  • Rubio T; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Spain.
  • Garcia-Cajide M; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain.
  • Menoyo S; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet de Llobregat, Barcelona, Spain.
  • Moreno V; Laboratory of Cancer Metabolism, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
  • Salazar R; Laboratory of Cancer Metabolism, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
  • Tauler A; Laboratory of Cancer Metabolism, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
  • Gentilella A; Laboratory of Cancer Metabolism, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
Sci Adv ; 7(48): eabg9275, 2021 Nov 26.
Article em En | MEDLINE | ID: mdl-34818049
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Espanha
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Espanha