Exosomal hsa_circ_0125310 promotes cell proliferation and fibrosis in diabetic nephropathy via sponging miR-422a and targeting the IGF1R/p38 axis.

Zhu, Yingchun; Zha, Fangfang; Tang, Bo; Ji, Ting-Ting; Li, Xiao-Ying; Feng, Linhong; Bai, Shou-Jun

Zhu, Yingchun; Zha, Fangfang; Tang, Bo; Ji, Ting-Ting; Li, Xiao-Ying; Feng, Linhong; Bai, Shou-Jun.

Afiliação

Zhu Y; Department of Nephrology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China.
Zha F; Department of Nephrology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China.
Tang B; Department of Nephrology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China.
Ji TT; Department of Nephrology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China.
Li XY; Department of Nephrology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China.
Feng L; Department of Nephrology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China.
Bai SJ; Department of Nephrology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China.

J Cell Mol Med ; 26(1): 151-162, 2022 01.

Article em En | MEDLINE | ID: mdl-34854210

Assuntos

Diabetes Mellitus; Nefropatias Diabéticas; MicroRNAs; RNA Circular; Proliferação de Células/genética; Nefropatias Diabéticas/genética; Nefropatias Diabéticas/metabolismo; Fibrose; Humanos; MicroRNAs/genética; MicroRNAs/metabolismo; RNA Circular/genética; Receptor IGF Tipo 1/genética; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

MCs; diabetic nephropathy; fibrosis; hsa_circ_0125310; proliferation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Diabetes Mellitus / Nefropatias Diabéticas / RNA Circular Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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