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E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models.
Bruun, Jarle; Eide, Peter W; Bergsland, Christian Holst; Bruck, Oscar; Svindland, Aud; Arjama, Mariliina; Välimäki, Katja; Bjørnslett, Merete; Guren, Marianne G; Kallioniemi, Olli; Nesbakken, Arild; Lothe, Ragnhild A; Pellinen, Teijo.
Afiliação
  • Bruun J; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Norway.
  • Eide PW; K.G. Jebsen Colorectal Cancer Research Centre, Division for Cancer Medicine, Oslo University Hospital, Norway.
  • Bergsland CH; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Norway.
  • Bruck O; K.G. Jebsen Colorectal Cancer Research Centre, Division for Cancer Medicine, Oslo University Hospital, Norway.
  • Svindland A; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Norway.
  • Arjama M; K.G. Jebsen Colorectal Cancer Research Centre, Division for Cancer Medicine, Oslo University Hospital, Norway.
  • Välimäki K; Hematology Research Unit Helsinki, University of Helsinki and Comprehensive Cancer Center, Helsinki University Hospital, Finland.
  • Bjørnslett M; K.G. Jebsen Colorectal Cancer Research Centre, Division for Cancer Medicine, Oslo University Hospital, Norway.
  • Guren MG; Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.
  • Kallioniemi O; Department of Pathology, Oslo University Hospital, Norway.
  • Nesbakken A; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Finland.
  • Lothe RA; Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Finland.
  • Pellinen T; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Norway.
Mol Oncol ; 16(12): 2312-2329, 2022 06.
Article em En | MEDLINE | ID: mdl-34890102
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Caderinas Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Noruega
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Caderinas Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Noruega