ß-Amyrin ameliorates diabetic nephropathy in mice and regulates the miR-181b-5p/HMGB2 axis in high glucose-stimulated HK-2 cells.

Xu, Wenhua; Zhang, Hongwu; Zhang, Qinfeng; Xu, Jialan

Xu, Wenhua; Zhang, Hongwu; Zhang, Qinfeng; Xu, Jialan.

Afiliação

Xu W; Preventive Treatment Center, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, Guangdong, China.
Zhang H; Department of Endocrinology, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, Guangdong, China.
Zhang Q; Department of Endocrinology, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, Guangdong, China.
Xu J; Preventive Treatment Center, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, Guangdong, China.

Environ Toxicol ; 37(3): 637-649, 2022 Mar.

Article em En | MEDLINE | ID: mdl-34894065

Assuntos

Diabetes Mellitus Experimental; Nefropatias Diabéticas; MicroRNAs; Animais; Nefropatias Diabéticas/genética; Glucose; Proteína HMGB2; Hibridização in Situ Fluorescente; Camundongos; MicroRNAs/genética; Ácido Oleanólico/análogos & derivados

Palavras-chave

DN; HMGB2; apoptosis; inflammatory response; miR-181b-5p; ß-amyrin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Diabetes Mellitus Experimental / Nefropatias Diabéticas Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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