Using Polyacrylamide Hydrogels to Model Physiological Aortic Stiffness Reveals that Microtubules Are Critical Regulators of Isolated Smooth Muscle Cell Morphology and Contractility.

Ahmed, Sultan; Johnson, Robert T; Solanki, Reesha; Afewerki, Teclino; Wostear, Finn; Warren, Derek T

Ahmed, Sultan; Johnson, Robert T; Solanki, Reesha; Afewerki, Teclino; Wostear, Finn; Warren, Derek T.

Afiliação

Ahmed S; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
Johnson RT; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
Solanki R; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
Afewerki T; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
Wostear F; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
Warren DT; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.

Front Pharmacol ; 13: 836710, 2022.

Article em En | MEDLINE | ID: mdl-35153800

Palavras-chave

actomyosin; contraction; matrix stiffness; microtubules; polyacrylamide hydrogel (PAH); traction force; vascular smooth muscle cell (VSMC)

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido