Clinical Study of a Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser with Different Parameters in the Treatment of Chloasma: A Randomized-Controlled Trial.
Photobiomodul Photomed Laser Surg
; 40(3): 183-188, 2022 Mar.
Article
em En
| MEDLINE
| ID: mdl-35298285
ABSTRACT
Objective:
To explore the clinical efficacy of a Q-switched neodymium-doped yttrium aluminum garnet (NdYAG) laser with different parameters in the treatment of chloasma.Methods:
In this study, 30 patients with chloasma, symmetrically distributed on the left and right sides of the face and who were treated with a Fayton Q-switched 1064 nm NdYAG laser, were recruited. The patients were randomly selected for the treatment of facial lesions on the left and right sides of the face using a spot diameter of 9 mm and an energy density of 0.8 J/cm2 on one side, and, on the opposite side, a spot diameter of 6 mm with an energy density of 1.2 J/cm2. The laser frequency was 5 Hz and treatment was conducted once every 7-10 days and repeated eight times as a course of treatment. At the end of the course of treatment, as well as 1, 3, and 6 months after treatment, front-facing images and 45° left- and right-side images were taken, respectively. The curative effect of the treatment was evaluated using the Melasma Area Severity Index (MASI) score.Results:
The results of this study showed that the total effective rate of a Fayton Q-switched 1064 nm NdYAG laser in the treatment of chloasma was 60%.Conclusions:
Using a Q-switched 1064 nm NdYAG laser represents a safe and effective approach for the treatment of chloasma. The therapeutic effects of the parameter sets, that is, a spot diameter of 9 mm and an energy density of 0.8 J/cm2, and a spot diameter of 6 mm with an energy density of 1.2 J/cm2, were similar. The treatment time and average effective times of the latter were relatively shortened. Clinical Trial Registration number researchregistry6799.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Terapia com Luz de Baixa Intensidade
/
Lasers de Estado Sólido
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Melanose
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China