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Effect of mild or moderate hepatic impairment on the pharmacokinetics of risdiplam.
Kletzl, Heidemarie; Ajmi, Hassan; Antys, Izabela; Heinig, Katja; Jaber, Birgit; Marbury, Thomas C; Young, Annie; Günther, Andreas.
Afiliação
  • Kletzl H; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Ajmi H; Covance Clinical Research Unit Limited, Leeds, UK.
  • Antys I; Covance Clinical Research Unit Limited, Leeds, UK.
  • Heinig K; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Jaber B; Pharma Development, Safety, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Marbury TC; Orlando Clinical Research Center, Orlando, Florida, USA.
  • Young A; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Welwyn, Welwyn Garden City, UK.
  • Günther A; Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
Br J Clin Pharmacol ; 88(8): 3749-3759, 2022 08.
Article em En | MEDLINE | ID: mdl-35301746

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatopatias Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatopatias Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça