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Differential assembly diversifies GABAA receptor structures and signalling.
Sente, Andrija; Desai, Rooma; Naydenova, Katerina; Malinauskas, Tomas; Jounaidi, Youssef; Miehling, Jonas; Zhou, Xiaojuan; Masiulis, Simonas; Hardwick, Steven W; Chirgadze, Dimitri Y; Miller, Keith W; Aricescu, A Radu.
Afiliação
  • Sente A; MRC Laboratory of Molecular Biology, Cambridge, UK. asente@mrc-lmb.cam.ac.uk.
  • Desai R; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Naydenova K; MRC Laboratory of Molecular Biology, Cambridge, UK.
  • Malinauskas T; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Jounaidi Y; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Miehling J; MRC Laboratory of Molecular Biology, Cambridge, UK.
  • Zhou X; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Masiulis S; MRC Laboratory of Molecular Biology, Cambridge, UK.
  • Hardwick SW; Materials and Structural Analysis Division, Thermo Fisher Scientific, Achtseweg Noord, Eindhoven, Netherlands.
  • Chirgadze DY; Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • Miller KW; Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • Aricescu AR; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. k_miller@helix.mgh.harvard.edu.
Nature ; 604(7904): 190-194, 2022 04.
Article em En | MEDLINE | ID: mdl-35355020

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Transdução de Sinais / Receptores de GABA-A Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Transdução de Sinais / Receptores de GABA-A Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido