Ketohexokinase-mediated fructose metabolism is lost in hepatocellular carcinoma and can be leveraged for metabolic imaging.

Tee, Sui Seng; Kim, Nathaniel; Cullen, Quinlan; Eskandari, Roozbeh; Mamakhanyan, Arsen; Srouji, Rami M; Chirayil, Rachel; Jeong, Sangmoo; Shakiba, Mojdeh; Kastenhuber, Edward R; Chen, Shuibing; Sigel, Carlie; Lowe, Scott W; Jarnagin, William R; Thompson, Craig B; Schietinger, Andrea; Keshari, Kayvan R

Tee, Sui Seng; Kim, Nathaniel; Cullen, Quinlan; Eskandari, Roozbeh; Mamakhanyan, Arsen; Srouji, Rami M; Chirayil, Rachel; Jeong, Sangmoo; Shakiba, Mojdeh; Kastenhuber, Edward R; Chen, Shuibing; Sigel, Carlie; Lowe, Scott W; Jarnagin, William R; Thompson, Craig B; Schietinger, Andrea; Keshari, Kayvan R.

Afiliação

Tee SS; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Kim N; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Cullen Q; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Eskandari R; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mamakhanyan A; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Srouji RM; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Chirayil R; Weill Cornell Medical College, New York, NY, USA.
Jeong S; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Shakiba M; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Kastenhuber ER; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Chen S; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sigel C; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lowe SW; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jarnagin WR; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Thompson CB; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Schietinger A; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Keshari KR; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Sci Adv ; 8(14): eabm7985, 2022 Apr 08.

Article em En | MEDLINE | ID: mdl-35385296

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos