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Decreased green autofluorescence of lung parenchyma is a biomarker for lung cancer tissues.
Zhang, Mingchao; Zhang, Jie; Teng, Haohua; Zhang, Qing; Xiang, Zhenzhen; Chang, Qing; Tao, Yue; Chu, Tianqing; Ying, Weihai.
Afiliação
  • Zhang M; Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
  • Zhang J; Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Teng H; Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Zhang Q; Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Xiang Z; Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Chang Q; Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Tao Y; Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
  • Chu T; Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Ying W; Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
J Biophotonics ; 15(8): e202200072, 2022 08.
Article em En | MEDLINE | ID: mdl-35429151
It is highly valuable to discover novel biomarkers for differentiating noninvasively the cancerous tissues from the nonneoplastic tissues of lung cancer. In current study, we determined the green autofluorescence (AF) of the pulmonary parenchyma of lung cancer patients, indicating that decreased green AF of pulmonary parenchyma may be the biomarker of this type: First, the green AF intensity of the cancerous tissues was significantly lower than that of the nonneoplastic tissues of the lung cancer patients; second, the green AF intensity of the nonneoplastic tissues of the lung squamous cell carcinoma was significantly lower than that of the lung adenocarcinoma; and third, "decreased green AF intensity" could be used for differentiating the nonneoplastic tissues and the cancerous tissues. Collectively, our study has suggested that decreased green AF of lung parenchyma is a biomarker for differentiating the cancerous tissues from the nonneoplastic tissues of lung cancer.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China