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The pathologic diagnosis of carcinoma in various tissues.
Avery, Alexandria; Alden, Jay; Kramish, Chelsea; Caballero, Corynne; Wright-Void, Chelsea; Bruner, Evelyn T.
Afiliação
  • Avery A; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States.
  • Alden J; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States.
  • Kramish C; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States.
  • Caballero C; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States.
  • Wright-Void C; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States.
  • Bruner ET; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States. Electronic address: brunere@musc.edu.
Adv Cancer Res ; 154: 1-14, 2022.
Article em En | MEDLINE | ID: mdl-35459466
ABSTRACT
Carcinoma is defined as cancer arising from the epithelial cells that line an organ or tissue. The most common carcinoma in males arises in the prostate and breast in females; while the most significant cause of cancer related mortality in the United States is carcinoma of the lung. Cancers typically begin as a clonal proliferation of cells that have acquired distinct mutations, which then progress to invasive carcinoma as the cells breach the underlying basement membrane associated with the tissue of origin. This transition to invasive carcinoma carries with it the potential to invade blood vessels or lymphatic channels and metastasize to lymph nodes or distant tissues resulting in increased morbidity and mortality. The histologic diagnosis of carcinoma is rendered based on both the cytologic and architectural features of the tumor, as well as the location of the proliferating cells and the interaction with the surrounding stromal elements.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Carcinoma Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Carcinoma Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos