Circ_NNT suppresses the apoptosis and inflammation in glucose-induced human retinal pigment epithelium by regulating miR-320b/TIMP3 axis in diabetic retinopathy.

Liu, Qian; Liu, Changgeng; Dong, Yangzeng; Li, Haijun; Ren, Jing

Liu, Qian; Liu, Changgeng; Dong, Yangzeng; Li, Haijun; Ren, Jing.

Afiliação

Liu Q; Henan Eye Institute, Henan Eye Hospital, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zhengzhou 450003, China. Electronic address: qianliuyk@163.com.
Liu C; Henan Eye Institute, Henan Eye Hospital, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zhengzhou 450003, China.
Dong Y; Henan Eye Institute, Henan Eye Hospital, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zhengzhou 450003, China.
Li H; Henan Eye Institute, Henan Eye Hospital, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zhengzhou 450003, China.
Ren J; Henan Eye Institute, Henan Eye Hospital, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zhengzhou 450003, China.

Clin Immunol ; 238: 109023, 2022 05.

Article em En | MEDLINE | ID: mdl-35477026

Assuntos

Diabetes Mellitus; Retinopatia Diabética; MicroRNAs; Apoptose/genética; Retinopatia Diabética/genética; Glucose/farmacologia; Humanos; Inflamação/genética; MicroRNAs/genética; MicroRNAs/metabolismo; Epitélio Pigmentado da Retina/metabolismo; Inibidor Tecidual de Metaloproteinase-3/genética; Inibidor Tecidual de Metaloproteinase-3/farmacologia

Palavras-chave

Apoptosis; Diabetic retinopathy; Inflammation; TIMP3; circ_NNT; miR-320b

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Diabetes Mellitus / Retinopatia Diabética Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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