A TLR4-independent critical role for CD14 in intracellular LPS sensing.

Vasudevan, Swathy O; Russo, Ashley J; Kumari, Puja; Vanaja, Sivapriya Kailasan; Rathinam, Vijay A

Vasudevan, Swathy O; Russo, Ashley J; Kumari, Puja; Vanaja, Sivapriya Kailasan; Rathinam, Vijay A.

Afiliação

Vasudevan SO; Department of Immunology, University of Connecticut Health School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA.
Russo AJ; Department of Immunology, University of Connecticut Health School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA.
Kumari P; Department of Immunology, University of Connecticut Health School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA.
Vanaja SK; Department of Immunology, University of Connecticut Health School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA. Electronic address: kailasanvanaja@uchc.edu.
Rathinam VA; Department of Immunology, University of Connecticut Health School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA. Electronic address: rathinam@uchc.edu.

Cell Rep ; 39(5): 110755, 2022 05 03.

Article em En | MEDLINE | ID: mdl-35508125

Assuntos

Inflamassomos; Lipopolissacarídeos; Animais; Caspases/metabolismo; Inflamassomos/metabolismo; Lipopolissacarídeos/metabolismo; Lipopolissacarídeos/farmacologia; Camundongos; Piroptose; Receptor 4 Toll-Like

Palavras-chave

CD14; CP: Immunology; LPS; caspase-11; gasdermin D; noncanonical inflammasome; pyroptosis; sepsis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lipopolissacarídeos / Inflamassomos Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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