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Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer.
De Santis, Maria Chiara; Gozzelino, Luca; Margaria, Jean Piero; Costamagna, Andrea; Ratto, Edoardo; Gulluni, Federico; Di Gregorio, Enza; Mina, Erica; Lorito, Nicla; Bacci, Marina; Lattanzio, Rossano; Sala, Gianluca; Cappello, Paola; Novelli, Francesco; Giovannetti, Elisa; Vicentini, Caterina; Andreani, Silvia; Delfino, Pietro; Corbo, Vincenzo; Scarpa, Aldo; Porporato, Paolo Ettore; Morandi, Andrea; Hirsch, Emilio; Martini, Miriam.
Afiliação
  • De Santis MC; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Gozzelino L; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Margaria JP; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Costamagna A; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Ratto E; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Gulluni F; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Di Gregorio E; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Mina E; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Lorito N; Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Firenze, Italy.
  • Bacci M; Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Firenze, Italy.
  • Lattanzio R; Department of Innovative Technologies in Medicine and Dentistry, Center for Advanced Studies and Technology (CAST), University "G. d'Annunzio", Chieti, Italy, Chieti, Italy.
  • Sala G; Department of Innovative Technologies in Medicine and Dentistry, Center for Advanced Studies and Technology (CAST), University "G. d'Annunzio", Chieti, Italy, Chieti, Italy.
  • Cappello P; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Novelli F; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
  • Giovannetti E; Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers, VU University, De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands.
  • Vicentini C; Cancer Pharmacology Lab, Fondazione Pisana per la Scienza, Pisa, Italy.
  • Andreani S; ARC-Net Research Centre, University of Verona, Verona, Italy.
  • Delfino P; Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
  • Corbo V; Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
  • Scarpa A; ARC-Net Research Centre, University of Verona, Verona, Italy.
  • Porporato PE; Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
  • Morandi A; ARC-Net Research Centre, University of Verona, Verona, Italy.
  • Hirsch E; Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
  • Martini M; Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
Gut ; 72(2): 360-371, 2023 02.
Article em En | MEDLINE | ID: mdl-35623884
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Fosfatidilinositol 3-Quinases / Carcinoma Ductal Pancreático / Everolimo / Inibidores de MTOR / Lipídeos / Lisossomos Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Fosfatidilinositol 3-Quinases / Carcinoma Ductal Pancreático / Everolimo / Inibidores de MTOR / Lipídeos / Lisossomos Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália