Pharmacogenetic testing in pediatric neurology: a pragmatic study evaluating clinician and patient perceptions.
Per Med
; 19(5): 423-434, 2022 09.
Article
em En
| MEDLINE
| ID: mdl-35830229
ABSTRACT
Aim:
To evaluate clinicians' and patients' perceptions of pharmacogenetic testing in a clinical setting. Materials &methods:
This is a pragmatic mixed-method prospective observational study. Hospital pharmacists and neurologists participated in focus groups regarding pharmacogenetic testing; patients who received pharmacogenetic testing and their community pharmacists completed surveys to assess their perception of these tests.Results:
Most study participants had a positive view of pharmacogenetic testing. Three major themes were identified from the focus groups receptiveness to pharmacogenetic testing, pharmacogenetic test characteristics and integrating pharmacogenetic tests into practice.Conclusion:
The views reported are encouraging for the eventual implementation of pharmacogenetics in practice. Local integration of these tests is an essential step to improve patient care through personalized medicine.
Genetic tests can help predict patients' response to medication. This study aimed to evaluate clinicians' and patients' perceptions of these genetic tests. Pediatric patients, with epilepsy, were tested and completed a survey to assess their perception of these tests. A survey was also completed by their community pharmacists, and virtual discussion groups were held with hospital pharmacists and neurologists. Most participants had a positive view of these tests, with three major themes identified from the discussion groups receptiveness to testing, test characteristics and integration of tests into practice. The views reported are encouraging for the eventual implementation of these tests in practice, an essential step to improve patient care through personalized medicine.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Testes Farmacogenômicos
/
Neurologia
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Canadá