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Selective targeting BMP2 and 4 in SMAD4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models.
Li, Shulin; Hoefnagel, Sanne J M; Read, Matthew; Meijer, Sybren; van Berge Henegouwen, Mark I; Gisbertz, Suzanne S; Bonora, Elena; Liu, David S H; Phillips, Wayne A; Calpe, Silvia; Correia, Ana C P; Sancho-Serra, Maria D C; Mattioli, Sandro; Krishnadath, Kausilia K.
Afiliação
  • Li S; Center for Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Hoefnagel SJM; Center for Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Read M; Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Meijer S; Department of Surgery, University of Melbourne, St Vincent's Hospital, Melbourne, Australia.
  • van Berge Henegouwen MI; Peter MacCallum Cancer Centre, Melbourne, Australia.
  • Gisbertz SS; Department of Pathology, Amsterdam UMC, Cancer Center Amsterdam, University of Amsterdam, Amsterdam, the Netherlands.
  • Bonora E; Department of Surgery, Amsterdam UMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Liu DSH; Department of Surgery, Amsterdam UMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Phillips WA; Department of Medical and Surgical Sciences, University of Bologna, U.O. Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
  • Calpe S; Upper Gatrointestinal Unit, Department of Surgery, Austin Health, Heidelberg, Victoria, Australia.
  • Correia ACP; Division of Cancer Research, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia.
  • Sancho-Serra MDC; Peter MacCallum Cancer Centre, Melbourne, Australia.
  • Mattioli S; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.
  • Krishnadath KK; Center for Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Cell Oncol (Dordr) ; 45(4): 639-658, 2022 Aug.
Article em En | MEDLINE | ID: mdl-35902550

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma / Proteína Morfogenética Óssea 2 / Proteína Morfogenética Óssea 4 Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma / Proteína Morfogenética Óssea 2 / Proteína Morfogenética Óssea 4 Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda