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Two mutations in the ORF1 of genotype 1 hepatitis E virus enhance virus replication and may associate with fulminant hepatic failure.
Wang, Bo; Tian, Debin; Sooryanarain, Harini; Mahsoub, Hassan M; Heffron, C Lynn; Hassebroek, Anna M; Meng, Xiang-Jin.
Afiliação
  • Wang B; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.
  • Tian D; Center for Emerging, Zoonotic and Arthropod-Borne Pathogens, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.
  • Sooryanarain H; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.
  • Mahsoub HM; Center for Emerging, Zoonotic and Arthropod-Borne Pathogens, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.
  • Heffron CL; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.
  • Hassebroek AM; Center for Emerging, Zoonotic and Arthropod-Borne Pathogens, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.
  • Meng XJ; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061.
Proc Natl Acad Sci U S A ; 119(34): e2207503119, 2022 08 23.
Article em En | MEDLINE | ID: mdl-35969750

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Hepatite E / Hepatite E / Falência Hepática Aguda Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Hepatite E / Hepatite E / Falência Hepática Aguda Idioma: En Ano de publicação: 2022 Tipo de documento: Article