From Double-Strand Break Recognition to Cell-Cycle Checkpoint Activation: High Content and Resolution Image Cytometry Unmasks 53BP1 Multiple Roles in DNA Damage Response and p53 Action.

Furia, Laura; Pelicci, Simone; Scanarini, Mirco; Pelicci, Pier Giuseppe; Faretta, Mario

Furia, Laura; Pelicci, Simone; Scanarini, Mirco; Pelicci, Pier Giuseppe; Faretta, Mario.

Afiliação

Furia L; Department of Experimental Oncology, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Pelicci S; Department of Experimental Oncology, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Scanarini M; Department of Experimental Oncology, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Pelicci PG; Department of Experimental Oncology, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Faretta M; Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy.

Int J Mol Sci ; 23(17)2022 Sep 05.

Article em En | MEDLINE | ID: mdl-36077590

Assuntos

Quebras de DNA de Cadeia Dupla; Proteína Supressora de Tumor p53; DNA/metabolismo; Dano ao DNA; Reparo do DNA; Citometria por Imagem; Proteína Supressora de Tumor p53/metabolismo; Proteína 1 de Ligação à Proteína Supressora de Tumor p53/metabolismo

Palavras-chave

53BP1; DNA damage response; cell-cycle; fluorescence microscopy; image analysis; image cytometry; p53

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Quebras de DNA de Cadeia Dupla Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália

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