Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls.

Wilson, Samantha L; Shen, Shu Yi; Harmon, Lauren; Burgener, Justin M; Triche, Tim; Bratman, Scott V; De Carvalho, Daniel D; Hoffman, Michael M

Wilson, Samantha L; Shen, Shu Yi; Harmon, Lauren; Burgener, Justin M; Triche, Tim; Bratman, Scott V; De Carvalho, Daniel D; Hoffman, Michael M.

Afiliação

Wilson SL; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Shen SY; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Harmon L; Van Andel Institute, Grand Rapids, MI, USA.
Burgener JM; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Triche T; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Bratman SV; Van Andel Institute, Grand Rapids, MI, USA.
De Carvalho DD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Hoffman MM; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

Cell Rep Methods ; 2(9): 100294, 2022 09 19.

Article em En | MEDLINE | ID: mdl-36160046

Assuntos

Ácidos Nucleicos Livres; Epigenoma; Genômica/métodos; Metilação de DNA; DNA/genética; Ácidos Nucleicos Livres/genética

Palavras-chave

DNA methylation; absolute quantification; batch effects; cell-free DNA; cell-free methylated DNA immunoprecipitation; cfDNA; cfMeDIP; early detection of cancer; liquid biopsy; minimally invasive testing; reference standards; spike-in controls

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Nucleicos Livres / Epigenoma Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google