Lenalidomide attenuates IMQ-induced inflammation in a mouse model of psoriasis.

Jia, Hai-Yan; Qiu, Hai-Ying; Zhang, Meng-Di; Hou, Jing-Jing; Zhou, Meng-Lu; Wu, Yan

Jia, Hai-Yan; Qiu, Hai-Ying; Zhang, Meng-Di; Hou, Jing-Jing; Zhou, Meng-Lu; Wu, Yan.

Afiliação

Jia HY; Department of Pharmacy, Air Force Medical Center, PLA, Beijing, China.
Qiu HY; Department of Pharmacy, Air Force Medical Center, PLA, Beijing, China.
Zhang MD; Department of Pharmacy, Air Force Medical Center, PLA, Beijing, China.
Hou JJ; Department of Pharmacy, Air Force Medical Center, PLA, Beijing, China; HeBei North University, Zhangjiakou, China.
Zhou ML; Department of Pharmacy, Air Force Medical Center, PLA, Beijing, China.
Wu Y; Department of Pharmacy, Air Force Medical Center, PLA, Beijing, China. Electronic address: wuyan2001@163.com.

Biomed Pharmacother ; 156: 113883, 2022 Dec.

Article em En | MEDLINE | ID: mdl-36270258

Assuntos

NF-kappa B; Psoríase; Animais; Camundongos; Modelos Animais de Doenças; Imiquimode/farmacologia; Inflamação/metabolismo; Lenalidomida; Camundongos Endogâmicos BALB C; Recidiva Local de Neoplasia/patologia; NF-kappa B/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Psoríase/induzido quimicamente; Psoríase/tratamento farmacológico; Pele; Microambiente Tumoral

Palavras-chave

AKT pathway; CD4; Lenalidomide; NF-κB pathway; Psoriasis; Transcriptome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psoríase / NF-kappa B Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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