Single-cell and bulk RNA sequencing reveal ligands and receptors associated with worse overall survival in serous ovarian cancer.

Carvalho, Robson Francisco; do Canto, Luisa Matos; Abildgaard, Cecilie; Aagaard, Mads Malik; Tronhjem, Monica Søgaard; Waldstrøm, Marianne; Jensen, Lars Henrik; Steffensen, Karina Dahl; Rogatto, Silvia Regina

Carvalho, Robson Francisco; do Canto, Luisa Matos; Abildgaard, Cecilie; Aagaard, Mads Malik; Tronhjem, Monica Søgaard; Waldstrøm, Marianne; Jensen, Lars Henrik; Steffensen, Karina Dahl; Rogatto, Silvia Regina.

Afiliação

Carvalho RF; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100, Vejle, Denmark. robson.carvalho@unesp.br.
do Canto LM; Institute of Regional Health Research, University of Southern Denmark, 5230, Odense, Denmark. robson.carvalho@unesp.br.
Abildgaard C; Department of Structural and Functional Biology - Institute of Bioscience, São Paulo State University (UNESP), 18.618-689, Botucatu, Brazil. robson.carvalho@unesp.br.
Aagaard MM; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100, Vejle, Denmark.
Tronhjem MS; Institute of Regional Health Research, University of Southern Denmark, 5230, Odense, Denmark.
Waldstrøm M; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100, Vejle, Denmark.
Jensen LH; Institute of Regional Health Research, University of Southern Denmark, 5230, Odense, Denmark.
Steffensen KD; Department of Clinical Genetics, University Hospital of Southern Denmark, 7100, Vejle, Denmark.
Rogatto SR; Department of Oncology, University Hospital of Southern Denmark, 7100, Vejle, Denmark.

Cell Commun Signal ; 20(1): 176, 2022 11 09.

Article em En | MEDLINE | ID: mdl-36352420

Assuntos

Neoplasias Ovarianas; Fosfatidilinositol 3-Quinases; Humanos; Feminino; Fosfatidilinositol 3-Quinases/metabolismo; Ligantes; Fibroblastos/metabolismo; Neoplasias Ovarianas/patologia; Microambiente Tumoral/genética; Análise de Sequência de RNA; RNA/metabolismo; Linhagem Celular Tumoral

Palavras-chave

Cancer-associated fibroblasts; Cellcell communication; Organoids; Serous ovarian cancer; Single-cell RNA-sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Fosfatidilinositol 3-Quinases Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Dinamarca

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