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Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3.
Shvartsbart, Artem; Roach, Jeremy J; Witten, Michael R; Koblish, Holly; Harris, Jennifer J; Covington, Maryanne; Hess, Rodrigo; Lin, Luping; Frascella, Michelle; Truong, Lisa; Leffet, Lynn; Conlen, Patricia; Beshad, Elham; Klabe, Ron; Katiyar, Kamna; Kaldon, Laura; Young-Sciame, Ruth; He, Xin; Petusky, Susan; Chen, Kwang-Jong; Horsey, April; Lei, Hsiang-Ting; Epling, Leslie B; Deller, Marc C; Vechorkin, Oleg; Yao, Wenqing.
Afiliação
  • Shvartsbart A; Prelude Therapeutics, Wilmington, Delaware 19803, United States.
  • Roach JJ; Proteovant Therapeutics, King of Prussia, Pennsylvania 19406, United States.
  • Witten MR; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Koblish H; Ikena Oncology, Boston, Massachusetts 02210, United States.
  • Harris JJ; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Covington M; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Hess R; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Lin L; WuXi AppTec, Philadelphia, Pennsylvania 19112, United States.
  • Frascella M; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Truong L; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Leffet L; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Conlen P; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Beshad E; Proteovant Therapeutics, King of Prussia, Pennsylvania 19406, United States.
  • Klabe R; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Katiyar K; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Kaldon L; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Young-Sciame R; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • He X; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Petusky S; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Chen KJ; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Horsey A; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Lei HT; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Epling LB; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Deller MC; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Vechorkin O; Incyte Corporation, Wilmington, Delaware 19803, United States.
  • Yao W; Synnovation Therapeutics, Wilmington, Delaware 19803, United States.
J Med Chem ; 65(22): 15433-15442, 2022 11 24.
Article em En | MEDLINE | ID: mdl-36356320
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Fatores de Crescimento de Fibroblastos / Inibidores de Proteínas Quinases / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Fatores de Crescimento de Fibroblastos / Inibidores de Proteínas Quinases / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos