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Isocitrate dehydrogenase 1 mutation drives leukemogenesis by PDGFRA activation due to insulator disruption in acute myeloid leukemia (AML).
Steinhäuser, Sophie; Silva, Patricia; Lenk, Lennart; Beder, Thomas; Hartmann, Alina; Hänzelmann, Sonja; Fransecky, Lars; Neumann, Martin; Bastian, Lorenz; Lipinski, Simone; Richter, Kathrin; Bultmann, Miriam; Hübner, Emely; Xia, Shuli; Röllig, Christoph; Vogiatzi, Fotini; Schewe, Denis Martin; Yumiceba, Veronica; Schultz, Kristin; Spielmann, Malte; Baldus, Claudia Dorothea.
Afiliação
  • Steinhäuser S; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Silva P; Department of Hematology and Oncology, Charité University Hospital, Berlin, Germany.
  • Lenk L; Department of Pediatrics I, ALL-BFM Study Group, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Beder T; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Hartmann A; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Hänzelmann S; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Fransecky L; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Neumann M; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Bastian L; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Lipinski S; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Richter K; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Bultmann M; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Hübner E; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Xia S; Department of Inner Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany.
  • Röllig C; Kennedy Krieger Institute, Baltimore, MD, USA.
  • Vogiatzi F; School of Medicine, Department of Neurology, Johns Hopkins University, Baltimore, MD, USA.
  • Schewe DM; Department of Internal Medicine I, University Hospital Carl-Gustav-Carus, Dresden, Germany.
  • Yumiceba V; Department of Pediatrics I, ALL-BFM Study Group, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Schultz K; Children´s Hospital, University Hospital Magdeburg, Magdeburg, Germany.
  • Spielmann M; Institute for Human Genetics, University Hospital Schleswig-Holstein, Lübeck, Germany.
  • Baldus CD; Institute for Human Genetics, University Hospital Schleswig-Holstein, Lübeck, Germany.
Leukemia ; 37(1): 134-142, 2023 01.
Article em En | MEDLINE | ID: mdl-36411356

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Isocitrato Desidrogenase Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Isocitrato Desidrogenase Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha