Majority of transferred mosaic embryos developed healthy live births revealed by a preclinical study using embryonic morphology assessment and noninvasive PGT-A on cell-free DNA in blastocoel fluid.

Cai, Lingbo; Zeng, Qiao; Gao, Chao; Wu, Wei; Shen, Jiandong; Wu, Bai-Lin; Wang, Dao Wu; Cui, Yugui; Liu, Jiayin

Cai, Lingbo; Zeng, Qiao; Gao, Chao; Wu, Wei; Shen, Jiandong; Wu, Bai-Lin; Wang, Dao Wu; Cui, Yugui; Liu, Jiayin.

Afiliação

Cai L; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Zeng Q; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Gao C; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Wu W; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China. weiwu77@163.com.
Shen J; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Wu BL; Institute of Biomedical Science, Fudan University, Children's Hospital and Shanghai Medical College, Fudan University, Shanghai, 2100032, China.
Wang DW; Departments of Pathology and Laboratory Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Cui Y; State Key Laboratory of Reproductive Medicine, Genetic Laboratory, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China. david37212@hotmail.com.
Liu J; State Key Laboratory of Reproductive Medicine, The Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.

J Assist Reprod Genet ; 39(11): 2483-2504, 2022 Nov.

Article em En | MEDLINE | ID: mdl-36422765

Assuntos

Aborto Espontâneo; Ácidos Nucleicos Livres; Diagnóstico Pré-Implantação; Gravidez; Feminino; Humanos; Diagnóstico Pré-Implantação/métodos; Nascido Vivo/genética; Ácidos Nucleicos Livres/genética; Aborto Espontâneo/genética; Blastocisto; Aneuploidia; Testes Genéticos/métodos; Fertilização in vitro

Palavras-chave

Blastocoel fluid (BF); Chorionic villus sampling (CVS); Embryo morphology assessment; In vitro fertilization (IVF); Mosaic embryo; Noninvasive preimplantation genetic testing for aneuploidy (niPGT-a)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aborto Espontâneo / Diagnóstico Pré-Implantação / Ácidos Nucleicos Livres Idioma: En Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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