7,8-Dihydroxy-3-(4'-hydroxyphenyl)coumarin inhibits invasion and migration of osteosarcoma cells.

Sugiyama, Yuki; Nakamura, Seikou; Tokuda, Yuichi; Nakano, Masakazu; Hattori, Yasunao; Nishiguchi, Hiroki; Toda, Yuki; Hosogi, Shigekuni; Yamashita, Masayuki; Tashiro, Kei; Ashihara, Eishi

Sugiyama, Yuki; Nakamura, Seikou; Tokuda, Yuichi; Nakano, Masakazu; Hattori, Yasunao; Nishiguchi, Hiroki; Toda, Yuki; Hosogi, Shigekuni; Yamashita, Masayuki; Tashiro, Kei; Ashihara, Eishi.

Afiliação

Sugiyama Y; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan.
Nakamura S; Department of Pharmacognosy, Kyoto Pharmaceutical University, Kyoto, Japan. Electronic address: naka@mb.kyoto-phu.ac.jp.
Tokuda Y; Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Nakano M; Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hattori Y; Center for Instrumental Analysis, Kyoto Pharmaceutical University, Kyoto, Japan.
Nishiguchi H; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan.
Toda Y; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan.
Hosogi S; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan.
Yamashita M; Department of Pharmaceutical Manufacturing Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan.
Tashiro K; Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Ashihara E; Department of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan. Electronic address: ash@mb.kyoto-phu.ac.jp.

Biochem Biophys Res Commun ; 638: 200-209, 2023 01 01.

Article em En | MEDLINE | ID: mdl-36462494

Assuntos

Neoplasias Ósseas; Osteossarcoma; Animais; Camundongos; Humanos; Movimento Celular; Linhagem Celular Tumoral; Recidiva Local de Neoplasia; Proteína cdc42 de Ligação ao GTP/metabolismo; Proteínas rho de Ligação ao GTP/metabolismo; Osteossarcoma/tratamento farmacológico; Osteossarcoma/patologia; Neoplasias Ósseas/tratamento farmacológico; Neoplasias Ósseas/patologia; Cumarínicos/farmacologia; Cumarínicos/uso terapêutico; Proteína rhoA de Ligação ao GTP/metabolismo; Proteínas rac1 de Ligação ao GTP/metabolismo

Palavras-chave

Coumarin derivatives; Invasion; Metastasis; Migration; Osteosarcoma; Rho small GTP-Binding proteins

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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