Vasohibin-1 promotes osteoclast differentiation in periodontal disease by stimulating the expression of RANKL in gingival fibroblasts.

Heo, Soon Chul; Kim, Yu Na; Keum, Bo Ram; Joo, Ji-Young; Bae, Moon-Kyoung; Kim, Hyung Joon

Heo, Soon Chul; Kim, Yu Na; Keum, Bo Ram; Joo, Ji-Young; Bae, Moon-Kyoung; Kim, Hyung Joon.

Afiliação

Heo SC; Department of Oral Physiology, Periodontal Diseases Signaling Network Research Center, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, Republic of Korea.
Kim YN; Department of Oral Physiology, Periodontal Diseases Signaling Network Research Center, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, Republic of Korea.
Keum BR; Department of Oral Physiology, Periodontal Diseases Signaling Network Research Center, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, Republic of Korea.
Joo JY; Department of Periodontology and Dental Research Institute, Pusan National University Dental Hospital, Yangsan, Republic of Korea.
Bae MK; Department of Oral Physiology, Periodontal Diseases Signaling Network Research Center, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, Republic of Korea.
Kim HJ; Department of Oral Physiology, Periodontal Diseases Signaling Network Research Center, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, Republic of Korea. Electronic address: hjoonkim@pusan.ac.kr.

Biochim Biophys Acta Mol Basis Dis ; 1869(3): 166632, 2023 03.

Article em En | MEDLINE | ID: mdl-36566872

Assuntos

Osteoclastos; Periodontite; Humanos; Osteoclastos/metabolismo; Diferenciação Celular; Proteínas Proto-Oncogênicas c-akt/metabolismo; Fator A de Crescimento do Endotélio Vascular/metabolismo; Fatores de Transcrição/metabolismo; Porphyromonas gingivalis/metabolismo; Periodontite/patologia; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo

Palavras-chave

Gingival fibroblasts; Osteoclastogenesis; Periodontal disease; Porphyromonas gingivalis; RANK ligand (RANKL); Vasohibin-1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Periodontite Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Periodontite Idioma: En Ano de publicação: 2023 Tipo de documento: Article