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SARS-CoV-2 viral entry and replication is impaired in Cystic Fibrosis airways due to ACE2 downregulation.
Bezzerri, Valentino; Gentili, Valentina; Api, Martina; Finotti, Alessia; Papi, Chiara; Tamanini, Anna; Boni, Christian; Baldisseri, Elena; Olioso, Debora; Duca, Martina; Tedesco, Erika; Leo, Sara; Borgatti, Monica; Volpi, Sonia; Pinton, Paolo; Cabrini, Giulio; Gambari, Roberto; Blasi, Francesco; Lippi, Giuseppe; Rimessi, Alessandro; Rizzo, Roberta; Cipolli, Marco.
Afiliação
  • Bezzerri V; Cystic Fibrosis Center of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
  • Gentili V; Section of Clinical Biochemistry, University of Verona, Verona, Italy.
  • Api M; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Ferrara, Italy.
  • Finotti A; Cystic Fibrosis Center of Ancona, Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona, Italy.
  • Papi C; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
  • Tamanini A; Center on Innovative Therapies for Cystic Fibrosis, University of Ferrara, Ferrara, Italy.
  • Boni C; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
  • Baldisseri E; Section of Molecular Pathology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
  • Olioso D; Cystic Fibrosis Center of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
  • Duca M; Cystic Fibrosis Center of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
  • Tedesco E; Section of Clinical Biochemistry, University of Verona, Verona, Italy.
  • Leo S; Cystic Fibrosis Center of Ancona, Azienda Ospedaliero Universitaria Ospedali Riuniti, Ancona, Italy.
  • Borgatti M; Cystic Fibrosis Center of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
  • Volpi S; Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
  • Pinton P; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
  • Cabrini G; Center on Innovative Therapies for Cystic Fibrosis, University of Ferrara, Ferrara, Italy.
  • Gambari R; Cystic Fibrosis Center of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
  • Blasi F; Center on Innovative Therapies for Cystic Fibrosis, University of Ferrara, Ferrara, Italy.
  • Lippi G; Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
  • Rimessi A; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
  • Rizzo R; Center on Innovative Therapies for Cystic Fibrosis, University of Ferrara, Ferrara, Italy.
  • Cipolli M; Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Nat Commun ; 14(1): 132, 2023 01 10.
Article em En | MEDLINE | ID: mdl-36627352
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Cística / Internalização do Vírus / Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 / COVID-19 Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Cística / Internalização do Vírus / Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 / COVID-19 Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália