Bacillus Calmette-Guérin pneumonitis after intravesical instillation: Report of two cases and a review of the literature.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
; 2023 Jan 02.
Article
em En
| MEDLINE
| ID: mdl-36628562
ABSTRACT
OBJECTIVE:
Intravesical administration of bacillus Calmette-Guérin is standard adjuvant treatment of non-muscle invasive bladder cancer. In spite of the fact that this immunotherapy is locoregional, there are still risk of some complications.METHODS:
We describe two cases of systemic BCG infection after intravesical administration of BCG vaccine in patients with early stage of bladder cancer.RESULTS:
Both patients suffered from systemic BCG infection manifesting as BCG pneumonitis. After standard therapy with antituberculotic agents, both of them fully recovered.CONCLUSION:
BCG infection can occur as a rare but potentially serious complication of this treatment procedure. Gravity of this side effect and its specific therapy require prompt and right diagnosis.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
República Tcheca