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Corrected T1 Mapping in Children and Young Adults With Autoimmune Liver Disease: Correlation With Histology.
Trout, Andrew T; Taylor, Amy E; Kasten, Jennifer L; Castro-Rojas, Cyd; Mahalingam, Neeraja; Miethke, Alexander G; Dillman, Jonathan R.
Afiliação
  • Trout AT; Department of Radiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH 45229.
  • Taylor AE; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of Cincinnati College of Medicine, Cincinnati, OH.
  • Kasten JL; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of Cincinnati College of Medicine, Cincinnati, OH.
  • Castro-Rojas C; Department of Pediatrics, Division of Pathology, University of Cincinnati College of Medicine, Cincinnati, OH.
  • Mahalingam N; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of Cincinnati College of Medicine, Cincinnati, OH.
  • Miethke AG; Department of Radiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH 45229.
  • Dillman JR; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of Cincinnati College of Medicine, Cincinnati, OH.
AJR Am J Roentgenol ; 220(6): 901-902, 2023 06.
Article em En | MEDLINE | ID: mdl-36629304
ABSTRACT
The purpose of this study was to assess relationships between liver-corrected T1 (cT1) values (adjusted for T2* effect, MRI system manufacturer, and field strength) and histologic inflammation and fibrosis in 35 participants (15 women and girls, 20 boys and men; median age, 16.0 years) with autoimmune liver disease. At multivariable analysis, inflammation score (ß = 15.5) and sex (ß = 56.0 [female]) were independent predictors of cT1, and fibrosis score (ß = 32.3) and age (ß = 5.5) were independent predictors of cT1 IQR. Liver T1 may have relevance for assessing liver inflammatory activity and fibrosis stage.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Hepatopatias Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Hepatopatias Idioma: En Ano de publicação: 2023 Tipo de documento: Article