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AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage.
Pei, Jin-Peng; Wang, Yue; Ma, Lan-Ping; Wang, Xin; Liu, Liang; Zhang, Yu; Jin, Rui; Ren, Zhi-Qiang; Deng, Yan; Shen, Jing-Kang; Meng, Tao; Yu, Ker.
Afiliação
  • Pei JP; Department of Pharmacology, Fudan University School of Pharmacy, Shanghai, 201203, China.
  • Wang Y; Department of Pharmacology, Fudan University School of Pharmacy, Shanghai, 201203, China.
  • Ma LP; Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Wang X; Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Liu L; Department of Pharmacology, Fudan University School of Pharmacy, Shanghai, 201203, China.
  • Zhang Y; Department of Pharmacology, Fudan University School of Pharmacy, Shanghai, 201203, China.
  • Jin R; Department of Pharmacology, Fudan University School of Pharmacy, Shanghai, 201203, China.
  • Ren ZQ; Department of Pharmacology, Fudan University School of Pharmacy, Shanghai, 201203, China.
  • Deng Y; Department of Pharmacology, Fudan University School of Pharmacy, Shanghai, 201203, China.
  • Shen JK; Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. jkshen@simm.ac.cn.
  • Meng T; Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. tmeng@simm.ac.cn.
  • Yu K; Department of Pharmacology, Fudan University School of Pharmacy, Shanghai, 201203, China. keryu@fudan.edu.cn.
Acta Pharmacol Sin ; 44(6): 1290-1303, 2023 Jun.
Article em En | MEDLINE | ID: mdl-36650292
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias de Mama Triplo Negativas / Neoplasias Pulmonares Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias de Mama Triplo Negativas / Neoplasias Pulmonares Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China