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Enhanced hexamerization of insulin via assembly pathway rerouting revealed by single particle studies.
Bohr, Freja; Bohr, Søren S-R; Mishra, Narendra Kumar; González-Foutel, Nicolás Sebastian; Pinholt, Henrik Dahl; Wu, Shunliang; Nielsen, Emilie Milan; Zhang, Min; Kjaergaard, Magnus; Jensen, Knud J; Hatzakis, Nikos S.
Afiliação
  • Bohr F; Department of Chemistry & Nanoscience Center, University of Copenhagen, Copenhagen, Denmark.
  • Bohr SS; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Mishra NK; Department of Chemistry & Nanoscience Center, University of Copenhagen, Copenhagen, Denmark.
  • González-Foutel NS; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Pinholt HD; Department of Chemistry & Nanoscience Center, University of Copenhagen, Copenhagen, Denmark.
  • Wu S; Department of Molecular Biology and Genetics, The Danish Research Institute for Translational Neuroscience (DANDRITE), Nordic EMBL Partnership for Molecular Medicine, and Center for Proteins in Memory PROMEMO, Danish National Research Foundation, Aarhus University, Aarhus, Denmark.
  • Nielsen EM; Department of Chemistry & Nanoscience Center, University of Copenhagen, Copenhagen, Denmark.
  • Zhang M; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Kjaergaard M; Physics Department, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Jensen KJ; Department of Chemistry & Nanoscience Center, University of Copenhagen, Copenhagen, Denmark.
  • Hatzakis NS; Department of Chemistry & Nanoscience Center, University of Copenhagen, Copenhagen, Denmark.
Commun Biol ; 6(1): 178, 2023 02 15.
Article em En | MEDLINE | ID: mdl-36792809
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Insulina Regular Humana / Insulina Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Insulina Regular Humana / Insulina Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca