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Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023.
Agergaard, Charlotte Nielsen; Porsbo, Lone Jannok; Sydenham, Thomas Vognbjerg; Hansen, Sanne Grønvall Kjær; Steinke, Kat; Larsen, Sanne Løkkegaard; Helgason, Kristján Orri; Hansen, Frank; Karstensen, Kasper Thystrup; Henius, Anna E; Holzknecht, Barbara Juliane; Søes, Lillian; Schønning, Kristian; Wang, Mikala; Ank, Nina; Halldórsdóttir, Anna Margrét; Guðlaugsson, Ólafur; Hammerum, Anette M; Kjerulf, Anne; Kristensen, Brian; Hasman, Henrik; Justesen, Ulrik Stenz.
Afiliação
  • Agergaard CN; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
  • Porsbo LJ; Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
  • Sydenham TV; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
  • Hansen SGK; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
  • Steinke K; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
  • Larsen SL; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
  • Helgason KO; Department of Clinical Microbiology, Landspitali University Hospital of Iceland, Reykjavik, Iceland.
  • Hansen F; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
  • Karstensen KT; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
  • Henius AE; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
  • Holzknecht BJ; Department of Clinical Microbiology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
  • Søes L; Department of Clinical Microbiology, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.
  • Schønning K; Department of Clinical Microbiology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
  • Wang M; Department of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.
  • Ank N; Department of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark.
  • Halldórsdóttir AM; Centre for Health Security and Communicable Disease Control, Directorate of Health, Reykjavik, Iceland.
  • Guðlaugsson Ó; Department of Internal Medicine, division of Infectious Diseases, Landspitali University Hospital of Iceland, Reykjavik, Iceland.
  • Hammerum AM; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
  • Kjerulf A; Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
  • Kristensen B; Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
  • Hasman H; Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
  • Justesen US; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.
Euro Surveill ; 28(9)2023 03.
Article em En | MEDLINE | ID: mdl-36862098
ABSTRACT
From October 2022 through January 2023, nine patients with NDM-5/OXA-48-carbapenemase-producing Enterobacter hormaechei ST79 were detected in Denmark and subsequently one patient in Iceland. There were no nosocomial links between patients, but they had all been treated with dicloxacillin capsules. An NDM-5/OXA-48-carbapenemase-producing E. hormaechei ST79, identical to patient isolates, was cultured from the surface of dicloxacillin capsules in Denmark, strongly implicating them as the source of the outbreak. Special attention is required to detect the outbreak strain in the microbiology laboratory.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Surtos de Doenças / Dicloxacilina País/Região como assunto: Europa Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Surtos de Doenças / Dicloxacilina País/Região como assunto: Europa Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca