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Assessment of metabolic stability and pharmacokinetics by LC-MS/MS and establishment of the safe dose of IMID-2, a novel anticancer molecule under drug discovery.
Kumar, S Pranush; Jadav, Tarang; Sahu, Amit Kumar; Ghosh Chowdhary, Moumita; Siwach, Ankit; Patel, Harit; Patel, Sagarkumar; Rajput, Niraj; Shard, Amit; Khairnar, Amit; Sengupta, Pinaki.
Afiliação
  • Kumar SP; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Jadav T; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Sahu AK; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Ghosh Chowdhary M; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Siwach A; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Patel H; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Patel S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Rajput N; Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Shard A; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Khairnar A; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.
  • Sengupta P; Department of Physiology, Faculty of Medicine, Masaryk University, 62500, Brno, Czech Republic.
Biomed Chromatogr ; 37(6): e5618, 2023 Jun.
Article em En | MEDLINE | ID: mdl-36882885
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectrometria de Massas em Tandem / Descoberta de Drogas Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectrometria de Massas em Tandem / Descoberta de Drogas Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia