Retinoic acid shows direct parasiticidal activity by targeting ergosterol pathway in <i>Leishmania donovani:</i> a potential therapeutic advancement.

Prakash, Satya; Rai, Ambak Kumar

Retinoic acid shows direct parasiticidal activity by targeting ergosterol pathway in Leishmania donovani: a potential therapeutic advancement.

Prakash, Satya; Rai, Ambak Kumar.

Afiliação

Prakash S; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, UP, India.
Rai AK; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, UP, India.

J Biomol Struct Dyn ; 41(23): 14473-14483, 2023.

Article em En | MEDLINE | ID: mdl-36974957

Assuntos

Leishmania donovani; Leishmaniose Visceral; Humanos; Tretinoína/farmacologia; Ergosterol/farmacologia; Ergosterol/metabolismo; Ergosterol/uso terapêutico; Leishmaniose Visceral/tratamento farmacológico; Leishmaniose Visceral/parasitologia; Colesterol

Palavras-chave

Visceral leishmaniasis; ergosterol; molecular docking; retinoic acid; sterol 24-C methyltransferase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leishmania donovani / Leishmaniose Visceral Idioma: En Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

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